| Appleton to Elkhorn (Wisconsin) | 3,795.86 mi (6,108.85 km) |
| Appleton to Elko (Nevada) | 4,817.35 mi (7,752.77 km) |
| Appleton to Elkridge (Maryland) | 3,505.04 mi (5,640.82 km) |
| Appleton to Elkton (Maryland) | 3,449.37 mi (5,551.23 km) |
| Appleton to Ellensburg (Washington) | 4,608.17 mi (7,416.14 km) |
| Appleton to Ellicott City (Maryland) | 3,504.83 mi (5,640.48 km) |
| Appleton to Elmhurst (Illinois) | 3,810.56 mi (6,132.50 km) |
| Appleton to Elmira (New York) | 3,375.71 mi (5,432.67 km) |
| Appleton to Elmont (New York) | 3,315.47 mi (5,335.74 km) |
| Appleton to Elmwood Park (Illinois) | 3,804.62 mi (6,122.95 km) |
| Appleton to Elmwood Park (New Jersey) | 3,322.83 mi (5,347.58 km) |
| Appleton to Elon (North Carolina) | 3,761.63 mi (6,053.76 km) |
| Appleton to Eloy (Arizona) | 5,135.75 mi (8,265.19 km) |
| Appleton to Elwood (New York) | 3,294.37 mi (5,301.78 km) |
| Appleton to Elyria (Ohio) | 3,613.85 mi (5,815.93 km) |
