| Appleton to El Sobrante (California) | 5,265.66 mi (8,474.26 km) |
| Appleton to Eldersburg (Maryland) | 3,503.66 mi (5,638.59 km) |
| Appleton to Elfers (Florida) | 4,285.80 mi (6,897.32 km) |
| Appleton to Elgin (Illinois) | 3,818.02 mi (6,144.51 km) |
| Appleton to Elizabeth (New Jersey) | 3,336.40 mi (5,369.42 km) |
| Appleton to Elizabeth City (North Carolina) | 3,621.19 mi (5,827.74 km) |
| Appleton to Elizabethton (Tennessee) | 3,858.56 mi (6,209.76 km) |
| Appleton to Elizabethtown (Kentucky) | 3,934.28 mi (6,331.61 km) |
| Appleton to Elizabethtown (Pennsylvania) | 3,455.17 mi (5,560.56 km) |
| Appleton to Elk City (Oklahoma) | 4,562.24 mi (7,342.21 km) |
| Appleton to Elk Grove (California) | 5,124.06 mi (8,246.38 km) |
| Appleton to Elk Grove Village (Illinois) | 3,807.19 mi (6,127.08 km) |
| Appleton to Elk Plain (Washington) | 4,654.37 mi (7,490.48 km) |
| Appleton to Elk River (Minnesota) | 3,850.56 mi (6,196.87 km) |
| Appleton to Elkhart (Indiana) | 3,746.03 mi (6,028.65 km) |
