| Appleton to Eggertsville (New York) | 3,414.35 mi (5,494.86 km) |
| Appleton to Egypt Lake-Leto (Florida) | 4,287.12 mi (6,899.46 km) |
| Appleton to El Cajon (California) | 5,310.90 mi (8,547.07 km) |
| Appleton to El Campo (Texas) | 4,770.99 mi (7,678.16 km) |
| Appleton to El Centro (California) | 5,266.05 mi (8,474.88 km) |
| Appleton to El Cerrito (California) | 5,179.87 mi (8,336.20 km) |
| Appleton to El Dorado (Arkansas) | 4,421.48 mi (7,115.68 km) |
| Appleton to El Dorado (Kansas) | 4,341.83 mi (6,987.50 km) |
| Appleton to El Dorado Hills (California) | 5,099.19 mi (8,206.36 km) |
| Appleton to El Mirage (Arizona) | 5,113.12 mi (8,228.78 km) |
| Appleton to El Monte (California) | 5,272.14 mi (8,484.69 km) |
| Appleton to El Paso (Texas) | 5,005.31 mi (8,055.26 km) |
| Appleton to El Paso de Robles (California) | 5,263.39 mi (8,470.61 km) |
| Appleton to El Reno (Oklahoma) | 4,500.33 mi (7,242.57 km) |
| Appleton to El Segundo (California) | 5,292.99 mi (8,518.24 km) |
