| Appleton to Desert Hot Springs (California) | 5,231.40 mi (8,419.13 km) |
| Appleton to DeSoto (Texas) | 4,613.56 mi (7,424.81 km) |
| Appleton to Destin (Florida) | 4,324.29 mi (6,959.27 km) |
| Appleton to Destrehan (Louisiana) | 4,501.02 mi (7,243.68 km) |
| Appleton to Detroit (Michigan) | 3,605.44 mi (5,802.39 km) |
| Appleton to Diamond Bar (California) | 5,269.67 mi (8,480.71 km) |
| Appleton to Diamond Springs (California) | 5,092.02 mi (8,194.81 km) |
| Appleton to Dickinson (North Dakota) | 4,085.18 mi (6,574.46 km) |
| Appleton to Dickinson (Texas) | 4,710.67 mi (7,581.10 km) |
| Appleton to Dickson (Tennessee) | 4,072.76 mi (6,554.47 km) |
| Appleton to Difficult Run (Virginia) | 3,542.63 mi (5,701.32 km) |
| Appleton to Dinuba (California) | 5,172.60 mi (8,324.49 km) |
| Appleton to Discovery Bay (California) | 5,159.99 mi (8,304.19 km) |
| Appleton to Dix Hills (New York) | 3,296.24 mi (5,304.78 km) |
| Appleton to Dixon (California) | 5,135.21 mi (8,264.32 km) |
