| Apex to Southern Pines (North Carolina) | 47.27 mi (76.07 km) |
| Apex to Southfield (Michigan) | 522.30 mi (840.57 km) |
| Apex to Southgate (Michigan) | 504.46 mi (811.86 km) |
| Apex to Southlake (Texas) | 1,058.45 mi (1,703.40 km) |
| Apex to Spanaway (Washington) | 2,354.67 mi (3,789.48 km) |
| Apex to Spanish Fork (Utah) | 1,801.09 mi (2,898.58 km) |
| Apex to Spanish Lake (Missouri) | 657.71 mi (1,058.48 km) |
| Apex to Spanish Springs (Nevada) | 2,227.75 mi (3,585.22 km) |
| Apex to Sparks (Nevada) | 2,230.85 mi (3,590.20 km) |
| Apex to Spartanburg (South Carolina) | 180.19 mi (289.99 km) |
| Apex to Spearfish (South Dakota) | 1,442.92 mi (2,322.16 km) |
| Apex to Speedway (Indiana) | 490.96 mi (790.13 km) |
| Apex to Spencer (Iowa) | 1,006.21 mi (1,619.34 km) |
| Apex to Spokane (Washington) | 2,126.60 mi (3,422.44 km) |
| Apex to Spokane Valley (Washington) | 2,117.43 mi (3,407.67 km) |
