| Antioch to Southern Pines (North Carolina) | 2,339.51 mi (3,765.07 km) |
| Antioch to Southfield (Michigan) | 2,038.61 mi (3,280.83 km) |
| Antioch to Southgate (Michigan) | 2,042.91 mi (3,287.75 km) |
| Antioch to Southlake (Texas) | 1,425.05 mi (2,293.40 km) |
| Antioch to Spanaway (Washington) | 630.88 mi (1,015.30 km) |
| Antioch to Spanish Fork (Utah) | 564.15 mi (907.91 km) |
| Antioch to Spanish Lake (Missouri) | 1,703.21 mi (2,741.05 km) |
| Antioch to Spanish Springs (Nevada) | 162.93 mi (262.21 km) |
| Antioch to Sparks (Nevada) | 157.14 mi (252.89 km) |
| Antioch to Spartanburg (South Carolina) | 2,208.60 mi (3,554.40 km) |
| Antioch to Spearfish (South Dakota) | 1,033.95 mi (1,663.98 km) |
| Antioch to Speedway (Indiana) | 1,903.38 mi (3,063.20 km) |
| Antioch to Spencer (Iowa) | 1,436.64 mi (2,312.04 km) |
| Antioch to Spokane (Washington) | 704.67 mi (1,134.06 km) |
| Antioch to Spokane Valley (Washington) | 707.57 mi (1,138.72 km) |
