| Annapolis to Southern Pines (North Carolina) | 306.02 mi (492.49 km) |
| Annapolis to Southfield (Michigan) | 428.53 mi (689.64 km) |
| Annapolis to Southgate (Michigan) | 416.40 mi (670.14 km) |
| Annapolis to Southlake (Texas) | 1,223.80 mi (1,969.51 km) |
| Annapolis to Spanaway (Washington) | 2,350.20 mi (3,782.29 km) |
| Annapolis to Spanish Fork (Utah) | 1,861.58 mi (2,995.92 km) |
| Annapolis to Spanish Lake (Missouri) | 736.45 mi (1,185.21 km) |
| Annapolis to Spanish Springs (Nevada) | 2,285.29 mi (3,677.82 km) |
| Annapolis to Sparks (Nevada) | 2,289.01 mi (3,683.81 km) |
| Annapolis to Spartanburg (South Carolina) | 408.45 mi (657.34 km) |
| Annapolis to Spearfish (South Dakota) | 1,451.41 mi (2,335.82 km) |
| Annapolis to Speedway (Indiana) | 523.17 mi (841.97 km) |
| Annapolis to Spencer (Iowa) | 1,011.06 mi (1,627.14 km) |
| Annapolis to Spokane (Washington) | 2,116.10 mi (3,405.54 km) |
| Annapolis to Spokane Valley (Washington) | 2,106.87 mi (3,390.67 km) |
