| Anchorage to Southern Pines (North Carolina) | 3,460.96 mi (5,569.87 km) |
| Anchorage to Southfield (Michigan) | 2,937.59 mi (4,727.59 km) |
| Anchorage to Southgate (Michigan) | 2,953.68 mi (4,753.49 km) |
| Anchorage to Southlake (Texas) | 3,002.22 mi (4,831.60 km) |
| Anchorage to Spanaway (Washington) | 1,434.25 mi (2,308.20 km) |
| Anchorage to Spanish Fork (Utah) | 2,141.71 mi (3,446.75 km) |
| Anchorage to Spanish Lake (Missouri) | 2,903.02 mi (4,671.97 km) |
| Anchorage to Spanish Springs (Nevada) | 1,938.48 mi (3,119.68 km) |
| Anchorage to Sparks (Nevada) | 1,942.19 mi (3,125.66 km) |
| Anchorage to Spartanburg (South Carolina) | 3,390.80 mi (5,456.96 km) |
| Anchorage to Spearfish (South Dakota) | 2,151.16 mi (3,461.96 km) |
| Anchorage to Speedway (Indiana) | 2,980.57 mi (4,796.77 km) |
| Anchorage to Spencer (Iowa) | 2,506.67 mi (4,034.10 km) |
| Anchorage to Spokane (Washington) | 1,553.04 mi (2,499.37 km) |
| Anchorage to Spokane Valley (Washington) | 1,559.39 mi (2,509.60 km) |
