| Amherst to University Place (Washington) | 2,010.00 mi (3,234.78 km) |
| Amherst to Upland (California) | 1,984.70 mi (3,194.07 km) |
| Amherst to Upper Arlington (Ohio) | 104.69 mi (168.49 km) |
| Amherst to Upper Grand Lagoon (Florida) | 800.49 mi (1,288.26 km) |
| Amherst to Upper Montclair (New Jersey) | 419.56 mi (675.21 km) |
| Amherst to Urbana (Illinois) | 324.72 mi (522.58 km) |
| Amherst to Urbana (Maryland) | 294.50 mi (473.95 km) |
| Amherst to Urbana (Ohio) | 119.79 mi (192.78 km) |
| Amherst to Urbandale (Iowa) | 597.32 mi (961.30 km) |
| Amherst to Utica (New York) | 376.73 mi (606.28 km) |
| Amherst to Uvalde (Texas) | 1,294.65 mi (2,083.54 km) |
| Amherst to Vacaville (California) | 2,098.87 mi (3,377.80 km) |
| Amherst to Vadnais Heights (Minnesota) | 600.86 mi (966.99 km) |
| Amherst to Vail (Arizona) | 1,694.76 mi (2,727.46 km) |
| Amherst to Valdosta (Georgia) | 731.40 mi (1,177.07 km) |
