| Americus to Emeryville (California) | 2,176.85 mi (3,503.29 km) |
| Americus to Emmaus (Pennsylvania) | 759.37 mi (1,222.09 km) |
| Americus to Emporia (Kansas) | 803.55 mi (1,293.20 km) |
| Americus to Encinitas (California) | 1,917.03 mi (3,085.16 km) |
| Americus to Endicott (New York) | 824.94 mi (1,327.61 km) |
| Americus to Endwell (New York) | 827.34 mi (1,331.47 km) |
| Americus to Englewood (Colorado) | 1,271.31 mi (2,045.97 km) |
| Americus to Englewood (Florida) | 370.02 mi (595.49 km) |
| Americus to Englewood (New Jersey) | 832.79 mi (1,340.24 km) |
| Americus to Englewood (Ohio) | 538.30 mi (866.32 km) |
| Americus to Enid (Oklahoma) | 833.95 mi (1,342.11 km) |
| Americus to Ennis (Texas) | 725.37 mi (1,167.37 km) |
| Americus to Ensley (Florida) | 209.33 mi (336.89 km) |
| Americus to Enterprise (Alabama) | 108.36 mi (174.40 km) |
| Americus to Enterprise (Nevada) | 1,788.06 mi (2,877.61 km) |
