| American Canyon to Scottsboro (Alabama) | 2,015.31 mi (3,243.33 km) |
| American Canyon to Scottsdale (Arizona) | 658.53 mi (1,059.80 km) |
| American Canyon to Scranton (Pennsylvania) | 2,453.80 mi (3,949.00 km) |
| American Canyon to Seabrook (Maryland) | 2,427.33 mi (3,906.41 km) |
| American Canyon to Seabrook (Texas) | 1,663.99 mi (2,677.94 km) |
| American Canyon to Seaford (New York) | 2,574.92 mi (4,143.93 km) |
| American Canyon to Seagoville (Texas) | 1,491.98 mi (2,401.11 km) |
| American Canyon to Seal Beach (California) | 385.01 mi (619.62 km) |
| American Canyon to Searcy (Arkansas) | 1,695.10 mi (2,728.00 km) |
| American Canyon to Seaside (California) | 110.25 mi (177.43 km) |
| American Canyon to SeaTac (Washington) | 640.14 mi (1,030.20 km) |
| American Canyon to Seattle (Washington) | 652.35 mi (1,049.86 km) |
| American Canyon to Sebastian (Florida) | 2,502.53 mi (4,027.43 km) |
| American Canyon to Sebring (Florida) | 2,459.80 mi (3,958.66 km) |
| American Canyon to Secaucus (New Jersey) | 2,543.90 mi (4,094.01 km) |
