| Alton to Southern Pines (North Carolina) | 3,904.99 mi (6,284.48 km) |
| Alton to Southfield (Michigan) | 3,729.85 mi (6,002.62 km) |
| Alton to Southgate (Michigan) | 3,739.74 mi (6,018.53 km) |
| Alton to Southlake (Texas) | 4,730.61 mi (7,613.19 km) |
| Alton to Spanaway (Washington) | 4,812.58 mi (7,745.11 km) |
| Alton to Spanish Fork (Utah) | 4,876.79 mi (7,848.44 km) |
| Alton to Spanish Lake (Missouri) | 4,171.00 mi (6,712.57 km) |
| Alton to Spanish Springs (Nevada) | 5,156.02 mi (8,297.82 km) |
| Alton to Sparks (Nevada) | 5,162.16 mi (8,307.70 km) |
| Alton to Spartanburg (South Carolina) | 4,021.16 mi (6,471.44 km) |
| Alton to Spearfish (South Dakota) | 4,386.80 mi (7,059.87 km) |
| Alton to Speedway (Indiana) | 3,968.74 mi (6,387.07 km) |
| Alton to Spencer (Iowa) | 4,148.99 mi (6,677.15 km) |
| Alton to Spokane (Washington) | 4,643.08 mi (7,472.31 km) |
| Alton to Spokane Valley (Washington) | 4,637.69 mi (7,463.64 km) |
