| Alton to Enumclaw (Washington) | 4,795.03 mi (7,716.86 km) |
| Alton to Ephrata (Pennsylvania) | 3,546.39 mi (5,707.36 km) |
| Alton to Erie (Colorado) | 4,656.77 mi (7,494.35 km) |
| Alton to Erie (Pennsylvania) | 3,619.69 mi (5,825.32 km) |
| Alton to Erlanger (Kentucky) | 3,939.10 mi (6,339.36 km) |
| Alton to Escanaba (Michigan) | 3,732.44 mi (6,006.78 km) |
| Alton to Escondido (California) | 5,442.91 mi (8,759.52 km) |
| Alton to Española (New Mexico) | 4,905.14 mi (7,894.05 km) |
| Alton to Essex (Maryland) | 3,595.72 mi (5,786.75 km) |
| Alton to Essex Junction (Vermont) | 3,241.81 mi (5,217.20 km) |
| Alton to Estelle (Louisiana) | 4,607.12 mi (7,414.44 km) |
| Alton to Estero (Florida) | 4,431.32 mi (7,131.52 km) |
| Alton to Euclid (Ohio) | 3,700.28 mi (5,955.02 km) |
| Alton to Eufaula (Alabama) | 4,300.61 mi (6,921.16 km) |
| Alton to Eugene (Oregon) | 5,005.06 mi (8,054.87 km) |
