| Alpena to Scottsboro (Alabama) | 733.71 mi (1,180.79 km) |
| Alpena to Scottsdale (Arizona) | 1,697.41 mi (2,731.73 km) |
| Alpena to Scranton (Pennsylvania) | 465.99 mi (749.94 km) |
| Alpena to Seabrook (Maryland) | 539.67 mi (868.52 km) |
| Alpena to Seabrook (Texas) | 1,242.78 mi (2,000.05 km) |
| Alpena to Seaford (New York) | 587.96 mi (946.23 km) |
| Alpena to Seagoville (Texas) | 1,107.71 mi (1,782.68 km) |
| Alpena to Seal Beach (California) | 1,988.13 mi (3,199.59 km) |
| Alpena to Searcy (Arkansas) | 807.31 mi (1,299.23 km) |
| Alpena to Seaside (California) | 2,067.71 mi (3,327.66 km) |
| Alpena to SeaTac (Washington) | 1,844.09 mi (2,967.78 km) |
| Alpena to Seattle (Washington) | 1,843.31 mi (2,966.52 km) |
| Alpena to Sebastian (Florida) | 1,205.79 mi (1,940.53 km) |
| Alpena to Sebring (Florida) | 1,220.76 mi (1,964.62 km) |
| Alpena to Secaucus (New Jersey) | 558.83 mi (899.35 km) |
