| Alpena to Oswego (Illinois) | 339.52 mi (546.41 km) |
| Alpena to Oswego (New York) | 361.08 mi (581.10 km) |
| Alpena to Otsego (Minnesota) | 495.72 mi (797.79 km) |
| Alpena to Ottawa (Illinois) | 373.42 mi (600.96 km) |
| Alpena to Ottawa (Kansas) | 754.07 mi (1,213.57 km) |
| Alpena to Ottumwa (Iowa) | 532.44 mi (856.88 km) |
| Alpena to Overland (Missouri) | 566.27 mi (911.33 km) |
| Alpena to Overland Park (Kansas) | 717.52 mi (1,154.74 km) |
| Alpena to Overlea (Maryland) | 529.80 mi (852.63 km) |
| Alpena to Oviedo (Florida) | 1,140.93 mi (1,836.14 km) |
| Alpena to Owasso (Oklahoma) | 886.96 mi (1,427.42 km) |
| Alpena to Owatonna (Minnesota) | 486.28 mi (782.59 km) |
| Alpena to Owensboro (Kentucky) | 540.07 mi (869.17 km) |
| Alpena to Owings Mills (Maryland) | 518.02 mi (833.67 km) |
| Alpena to Owosso (Michigan) | 148.19 mi (238.48 km) |
