| Aliso Viejo to Superior (Colorado) | 821.55 mi (1,322.16 km) |
| Aliso Viejo to Superior (Wisconsin) | 1,618.13 mi (2,604.12 km) |
| Aliso Viejo to Surprise (Arizona) | 303.65 mi (488.68 km) |
| Aliso Viejo to Susanville (California) | 498.69 mi (802.56 km) |
| Aliso Viejo to Sussex (Wisconsin) | 1,718.27 mi (2,765.29 km) |
| Aliso Viejo to Suwanee (Georgia) | 1,923.74 mi (3,095.97 km) |
| Aliso Viejo to Swansea (Illinois) | 1,580.68 mi (2,543.86 km) |
| Aliso Viejo to Sweetwater (Florida) | 2,293.00 mi (3,690.23 km) |
| Aliso Viejo to Sweetwater (Texas) | 1,005.09 mi (1,617.54 km) |
| Aliso Viejo to Sycamore (Illinois) | 1,679.45 mi (2,702.82 km) |
| Aliso Viejo to Sylacauga (Alabama) | 1,808.78 mi (2,910.94 km) |
| Aliso Viejo to Sylvania (Ohio) | 1,929.96 mi (3,105.97 km) |
| Aliso Viejo to Syosset (New York) | 2,458.13 mi (3,955.98 km) |
| Aliso Viejo to Syracuse (New York) | 2,321.44 mi (3,736.00 km) |
| Aliso Viejo to Syracuse (Utah) | 604.37 mi (972.64 km) |
