| Aliso Viejo to St. Simons (Georgia) | 2,116.37 mi (3,405.96 km) |
| Aliso Viejo to Stafford (Texas) | 1,329.77 mi (2,140.07 km) |
| Aliso Viejo to Stallings (North Carolina) | 2,105.16 mi (3,387.92 km) |
| Aliso Viejo to Stamford (Connecticut) | 2,454.29 mi (3,949.80 km) |
| Aliso Viejo to Stanford (California) | 364.52 mi (586.64 km) |
| Aliso Viejo to Stanton (California) | 21.56 mi (34.69 km) |
| Aliso Viejo to Star (Idaho) | 702.62 mi (1,130.75 km) |
| Aliso Viejo to Starkville (Mississippi) | 1,659.22 mi (2,670.25 km) |
| Aliso Viejo to State College (Pennsylvania) | 2,230.52 mi (3,589.67 km) |
| Aliso Viejo to Staten Island (New York) | 2,425.02 mi (3,902.69 km) |
| Aliso Viejo to Statesboro (Georgia) | 2,074.21 mi (3,338.11 km) |
| Aliso Viejo to Statesville (North Carolina) | 2,087.39 mi (3,359.33 km) |
| Aliso Viejo to Staunton (Virginia) | 2,172.19 mi (3,495.80 km) |
| Aliso Viejo to Steamboat Springs (Colorado) | 766.42 mi (1,233.43 km) |
| Aliso Viejo to Steiner Ranch (Texas) | 1,181.53 mi (1,901.49 km) |
