| Alexandroupoli to Southern Pines (North Carolina) | 5,363.99 mi (8,632.52 km) |
| Alexandroupoli to Southfield (Michigan) | 5,181.72 mi (8,339.18 km) |
| Alexandroupoli to Southgate (Michigan) | 5,192.29 mi (8,356.18 km) |
| Alexandroupoli to Southlake (Texas) | 6,179.00 mi (9,944.14 km) |
| Alexandroupoli to Spanaway (Washington) | 6,055.80 mi (9,745.87 km) |
| Alexandroupoli to Spanish Fork (Utah) | 6,238.91 mi (10,040.55 km) |
| Alexandroupoli to Spanish Lake (Missouri) | 5,619.96 mi (9,044.46 km) |
| Alexandroupoli to Spanish Springs (Nevada) | 6,466.84 mi (10,407.38 km) |
| Alexandroupoli to Sparks (Nevada) | 6,473.10 mi (10,417.45 km) |
| Alexandroupoli to Spartanburg (South Carolina) | 5,481.05 mi (8,820.90 km) |
| Alexandroupoli to Spearfish (South Dakota) | 5,766.82 mi (9,280.79 km) |
| Alexandroupoli to Speedway (Indiana) | 5,421.97 mi (8,725.82 km) |
| Alexandroupoli to Spencer (Iowa) | 5,570.65 mi (8,965.09 km) |
| Alexandroupoli to Spokane (Washington) | 5,920.82 mi (9,528.63 km) |
| Alexandroupoli to Spokane Valley (Washington) | 5,916.90 mi (9,522.33 km) |
