| Aiken to Southern Pines (North Carolina) | 175.35 mi (282.20 km) |
| Aiken to Southfield (Michigan) | 623.70 mi (1,003.75 km) |
| Aiken to Southgate (Michigan) | 604.72 mi (973.20 km) |
| Aiken to Southlake (Texas) | 891.32 mi (1,434.45 km) |
| Aiken to Spanaway (Washington) | 2,307.57 mi (3,713.68 km) |
| Aiken to Spanish Fork (Utah) | 1,706.87 mi (2,746.94 km) |
| Aiken to Spanish Lake (Missouri) | 596.02 mi (959.21 km) |
| Aiken to Spanish Springs (Nevada) | 2,130.56 mi (3,428.80 km) |
| Aiken to Sparks (Nevada) | 2,133.12 mi (3,432.92 km) |
| Aiken to Spartanburg (South Carolina) | 98.34 mi (158.27 km) |
| Aiken to Spearfish (South Dakota) | 1,400.03 mi (2,253.13 km) |
| Aiken to Speedway (Indiana) | 499.89 mi (804.50 km) |
| Aiken to Spencer (Iowa) | 983.05 mi (1,582.07 km) |
| Aiken to Spokane (Washington) | 2,087.28 mi (3,359.16 km) |
| Aiken to Spokane Valley (Washington) | 2,078.28 mi (3,344.67 km) |
