| Agrigento to Southern Pines (North Carolina) | 4,947.65 mi (7,962.48 km) |
| Agrigento to Southfield (Michigan) | 4,847.25 mi (7,800.89 km) |
| Agrigento to Southgate (Michigan) | 4,855.11 mi (7,813.55 km) |
| Agrigento to Southlake (Texas) | 5,847.65 mi (9,410.89 km) |
| Agrigento to Spanaway (Washington) | 6,002.24 mi (9,659.67 km) |
| Agrigento to Spanish Fork (Utah) | 6,061.03 mi (9,754.28 km) |
| Agrigento to Spanish Lake (Missouri) | 5,291.56 mi (8,515.94 km) |
| Agrigento to Spanish Springs (Nevada) | 6,347.73 mi (10,215.69 km) |
| Agrigento to Sparks (Nevada) | 6,353.86 mi (10,225.55 km) |
| Agrigento to Spartanburg (South Carolina) | 5,075.73 mi (8,168.60 km) |
| Agrigento to Spearfish (South Dakota) | 5,567.18 mi (8,959.51 km) |
| Agrigento to Speedway (Indiana) | 5,079.84 mi (8,175.21 km) |
| Agrigento to Spencer (Iowa) | 5,307.03 mi (8,540.84 km) |
| Agrigento to Spokane (Washington) | 5,835.16 mi (9,390.78 km) |
| Agrigento to Spokane Valley (Washington) | 5,829.83 mi (9,382.21 km) |
